HPK1 Associates with SKAP-HOM to Negatively Regulate Rap1-Mediated B-Lymphocyte Adhesion
HPK1 Associates with SKAP-HOM to Negatively Regulate Rap1-Mediated B-Lymphocyte Adhesion
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Hematopoietic progenitor kinase 1 (HPK1) is a Ste20-related serine/threonine kinase activated by a range of environmental stimuli including genotoxic stress, growth factors, inflammatory cytokines and antigen receptor triggering. Being inducibly recruited to membrane-proximal signalling scaffolds to regulate NFAT, AP-1 and NFkappaB-mediated gene tr...
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Full title
HPK1 Associates with SKAP-HOM to Negatively Regulate Rap1-Mediated B-Lymphocyte Adhesion
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TN_cdi_plos_journals_1292200357
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292200357
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0012468