PARP1 Gene Knock-Out Increases Resistance to Retinal Degeneration without Affecting Retinal Function
PARP1 Gene Knock-Out Increases Resistance to Retinal Degeneration without Affecting Retinal Function
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Author / Creator
Faculty of Medicine , Department of Clinical Sciences, Lund , Medicinska fakulteten , Sektion IV , Lund University , Section IV , Oftalmologi, Lund , Institutionen för kliniska vetenskaper, Lund , Ophthalmology, Lund , Lunds universitet , Sahaboglu, Ayse , Tanimoto, Naoyuki , Kaur, Jasvir , Sancho-Pelluz, Javier , Huber, Gesine , Fahl, Edda , Arango-Gonzalez, Blanca , Zrenner, Eberhart , Ekström, Per , Löwenheim, Hubert , Seeliger, Mathias and Paquet-Durand, François
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Retinitis pigmentosa (RP) is a group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness in humans. Previously, excessive activation of enzymes belonging to the poly-ADP-ribose polymerase (PARP) group was shown to be involved in photoreceptor degeneration in the human homologous rd1 mouse model for RP. Since there...
Alternative Titles
Full title
PARP1 Gene Knock-Out Increases Resistance to Retinal Degeneration without Affecting Retinal Function
Authors, Artists and Contributors
Author / Creator
Department of Clinical Sciences, Lund
Medicinska fakulteten
Sektion IV
Lund University
Section IV
Oftalmologi, Lund
Institutionen för kliniska vetenskaper, Lund
Ophthalmology, Lund
Lunds universitet
Sahaboglu, Ayse
Tanimoto, Naoyuki
Kaur, Jasvir
Sancho-Pelluz, Javier
Huber, Gesine
Fahl, Edda
Arango-Gonzalez, Blanca
Zrenner, Eberhart
Ekström, Per
Löwenheim, Hubert
Seeliger, Mathias
Paquet-Durand, François
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1292203949
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292203949
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0015495
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