Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection...
Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically targeted by epigenetic (DNA methylation) signatures in the place...
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Full title
Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome
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TN_cdi_plos_journals_1292206483
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292206483
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0015069