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Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection...

Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292206483

Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome

About this item

Full title

Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-11, Vol.5 (11), p.e15069-e15069

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Noninvasive prenatal diagnosis of fetal aneuploidy by maternal plasma analysis is challenging owing to the low fractional and absolute concentrations of fetal DNA in maternal plasma. Previously, we demonstrated for the first time that fetal DNA in maternal plasma could be specifically targeted by epigenetic (DNA methylation) signatures in the place...

Alternative Titles

Full title

Systematic identification of placental epigenetic signatures for the noninvasive prenatal detection of Edwards syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292206483

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292206483

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0015069

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