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Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292253266

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

About this item

Full title

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-10, Vol.5 (10), p.e13131

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Recently, there has been a surge of interest in developing compounds selectively targeting mitochondria for the treatment of neoplasms. The critical role of mitochondria in cellular metabolism and respiration supports this therapeutic rationale. Dysfunction in the processes of energy production and metabolism contributes to attenuation of response...

Alternative Titles

Full title

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292253266

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292253266

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0013131

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