Modulation of Cell Signaling Networks after CTLA4 Blockade in Patients with Metastatic Melanoma
Modulation of Cell Signaling Networks after CTLA4 Blockade in Patients with Metastatic Melanoma
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The effects on cell signalling networks upon blockade of cytotoxic T lymphocyte-associated antigen-4 (CTLA4) using the monoclonal antibody tremelimumab were studied in peripheral blood mononuclear cell (PBMC) samples from patients with metastatic melanoma.
Findings Intracellular flow cytometry was used to detect phosphorylated (p) signaling mole...
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Full title
Modulation of Cell Signaling Networks after CTLA4 Blockade in Patients with Metastatic Melanoma
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TN_cdi_plos_journals_1292287252
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292287252
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0012711
