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Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to defi...

Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to defi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292289982

Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells

About this item

Full title

Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-08, Vol.5 (8), p.e12101-e12101

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Stem cell-derived hepatocytes may be an alternative cell source to treat liver diseases or to be used for pharmacological purposes. We developed a protocol that mimics mammalian liver development, to differentiate cells with pluripotent characteristics to hepatocyte-like cells. The protocol supports the stepwise differentiation of human embryonic s...

Alternative Titles

Full title

Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292289982

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292289982

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0012101

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