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Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-med...

Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-med...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292297579

Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells

About this item

Full title

Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-07, Vol.5 (7), p.e11708-e11708

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

TCR stimulation leads to an increase in cellular adhesion among other outcomes. The adhesion and degranulation promoting adapter protein (ADAP) is known to be rapidly phosphorylated after T cell stimulation and relays the TCR signal to adhesion molecules of the integrin family. While three tyrosine phosphorylation sites have been characterized bioc...

Alternative Titles

Full title

Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292297579

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292297579

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0011708

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