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A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Spec...

A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Spec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292422196

A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Specific Expression and Risk of Myocardial Infarction

About this item

Full title

A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Specific Expression and Risk of Myocardial Infarction

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-03, Vol.6 (3), p.e17652-e17652

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The TNFSF4/TNFRSF4 system, along with several other receptor-ligand pairs, is involved in the recruitment and activation of T-cells and is therefore tentatively implicated in atherosclerosis and acute coronary syndromes. We have previously shown that genetic variants in TNFSF4 are associated with myocardial infarction (MI) in women. This prompted f...

Alternative Titles

Full title

A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Specific Expression and Risk of Myocardial Infarction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292422196

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292422196

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0017652

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