Protection of Macaques with Diverse MHC Genotypes against a Heterologous SIV by Vaccination with a D...
Protection of Macaques with Diverse MHC Genotypes against a Heterologous SIV by Vaccination with a Deglycosylated Live-Attenuated SIV
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Author / Creator
Sugimoto, Chie , Watanabe, Satoru , Naruse, Taeko , Kajiwara, Eiji , Shiino, Teiichiro , Umano, Natsuko , Ueda, Kayoko , Sato, Hirotaka , Ohgimoto, Shinji , Hirsch, Vanessa , Villinger, Francois , Ansari, Aftab A. , Kimura, Akinori , Miyazawa, Masaaki , Suzuki, Yasuo , Yamamoto, Naoki , Nagai, Yoshiyuki and Mori, Kazuyasu
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
HIV vaccine development has been hampered by issues such as undefined correlates of protection and extensive diversity of HIV. We addressed these issues using a previously established SIV-macaque model in which SIV mutants with deletions of multiple gp120 N-glycans function as potent live attenuated vaccines to induce near-sterile immunity against...
Alternative Titles
Full title
Protection of Macaques with Diverse MHC Genotypes against a Heterologous SIV by Vaccination with a Deglycosylated Live-Attenuated SIV
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Record Identifier
TN_cdi_plos_journals_1292425662
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292425662
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0011678
