Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Matrix metalloproteinases (MMPs) may have pro and antifibrotic roles within the lungs, due to its ability to modulate collagen turnover and immune mediators. MMP-8 is a collagenase that also cleaves a number of cytokines and chemokines.
To evaluate its relevance in lung fibrosis, wildtype and Mmp8(-/-) mice were treated with either intratracheal...
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Full title
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10
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TN_cdi_plos_journals_1292440080
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292440080
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0013242
