PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship b...
PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma
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Author / Creator
Bachetti, Tiziana , Di Paolo, Daniela , Di Lascio, Simona , Mirisola, Valentina , Brignole, Chiara , Bellotti, Marta , Caffa, Irene , Ferraris, Chiara , Fiore, Michele , Fornasari, Diego , Chiarle, Roberto , Borghini, Silvia , Pfeffer, Ulrich , Ponzoni, Mirco , Ceccherini, Isabella and Perri, Patrizia
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous and complex genetic etiology has been confirmed with the identification of mutations in two genes, encoding for the receptor tyrosine kinase Anaplastic Lymphoma Kinase (ALK) and the transcr...
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Full title
PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma
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TN_cdi_plos_journals_1292441846
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292441846
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0013108