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PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship b...

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292441846

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma

About this item

Full title

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-10, Vol.5 (10), p.e13108

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Neuroblastoma (NB) is a severe pediatric tumor originating from neural crest derivatives and accounting for 15% of childhood cancer mortality. The heterogeneous and complex genetic etiology has been confirmed with the identification of mutations in two genes, encoding for the receptor tyrosine kinase Anaplastic Lymphoma Kinase (ALK) and the transcr...

Alternative Titles

Full title

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292441846

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292441846

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0013108

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