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A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292617244

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

About this item

Full title

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-03, Vol.6 (3), p.e18142

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome. The LGI1 gene seems to have a role on the transmission of neuronal messages but the exact molecular mechanism remains unclear. In contrast to other gene...

Alternative Titles

Full title

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292617244

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292617244

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0018142

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