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Hyperleptinemia Is Required for the Development of Leptin Resistance

Hyperleptinemia Is Required for the Development of Leptin Resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292633587

Hyperleptinemia Is Required for the Development of Leptin Resistance

About this item

Full title

Hyperleptinemia Is Required for the Development of Leptin Resistance

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-06, Vol.5 (6), p.e11376-e11376

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Leptin regulates body weight by signaling to the brain the availability of energy stored as fat. This negative feedback loop becomes disrupted in most obese individuals, resulting in a state known as leptin resistance. The physiological causes of leptin resistance remain poorly understood. Here we test the hypothesis that hyperleptinemia is require...

Alternative Titles

Full title

Hyperleptinemia Is Required for the Development of Leptin Resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292633587

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292633587

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0011376

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