Hyperleptinemia Is Required for the Development of Leptin Resistance
Hyperleptinemia Is Required for the Development of Leptin Resistance
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Leptin regulates body weight by signaling to the brain the availability of energy stored as fat. This negative feedback loop becomes disrupted in most obese individuals, resulting in a state known as leptin resistance. The physiological causes of leptin resistance remain poorly understood. Here we test the hypothesis that hyperleptinemia is require...
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Full title
Hyperleptinemia Is Required for the Development of Leptin Resistance
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TN_cdi_plos_journals_1292633587
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292633587
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0011376