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Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer c...

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292657282

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability

About this item

Full title

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-09, Vol.5 (9), p.e12661

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The Y-box binding protein-1 (YB-1) is an oncogenic transcription/translation factor that is activated by phosphorylation at S102 whereby it induces the expression of growth promoting genes such as EGFR and HER-2. We recently illustrated by an in vitro kinase assay that a novel peptide to YB-1 was highly phosphorylated by the serine/threonine p90 S6...

Alternative Titles

Full title

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292657282

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292657282

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0012661

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