Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage
Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Previously, we reported that Galactoxylomannan (GalXM) activates the extrinsic and intrinsic apoptotic pathways through an interaction with the glycoreceptors on T cells. In this study we establish the role of the glycoreceptor CD45 in GalXM-induced T cell apoptosis, using CD45(+/+) and CD45(-/-) cell lines, derived from BW5147 murine T cell lympho...
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Full title
Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage
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TN_cdi_plos_journals_1292835334
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292835334
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0012720