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Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage

Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292835334

Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage

About this item

Full title

Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-09, Vol.5 (9), p.e12720-e12720

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Previously, we reported that Galactoxylomannan (GalXM) activates the extrinsic and intrinsic apoptotic pathways through an interaction with the glycoreceptors on T cells. In this study we establish the role of the glycoreceptor CD45 in GalXM-induced T cell apoptosis, using CD45(+/+) and CD45(-/-) cell lines, derived from BW5147 murine T cell lympho...

Alternative Titles

Full title

Role of CD45 signaling pathway in galactoxylomannan-induced T cell damage

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1292835334

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292835334

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0012720

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