Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferat...
Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Estrogen is a key regulator of normal function of female reproductive system and plays a pivotal role in the development and progression of breast cancer. Here, we demonstrate that JMJD2B (also known as KDM4B) constitutes a key component of the estrogen signaling pathway. JMJD2B is expressed in a high proportion of human breast tumors, and that exp...
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Full title
Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development
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TN_cdi_plos_journals_1292884801
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1292884801
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0017830
