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Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activ...

Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activ...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1293660349

Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1

About this item

Full title

Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-01, Vol.6 (1), p.e16234

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The cellular and molecular mechanisms of tumour response following chemotherapy are largely unknown. We found that low dose anti-tumour agents up-regulate early growth response 1 (EGR1) expression. EGR1 is a member of the immediate-early gene group of transcription factors which modulate transcription of multiple genes involved in cell proliferatio...

Alternative Titles

Full title

Suppression of osteosarcoma cell invasion by chemotherapy is mediated by urokinase plasminogen activator activity via up-regulation of EGR1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1293660349

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1293660349

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0016234

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