HPRT Deficiency Coordinately Dysregulates Canonical Wnt and Presenilin-1 Signaling: A Neuro-Developm...
HPRT Deficiency Coordinately Dysregulates Canonical Wnt and Presenilin-1 Signaling: A Neuro-Developmental Regulatory Role for a Housekeeping Gene?
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United States: Public Library of Science
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English
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United States: Public Library of Science
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We have used microarray-based methods of global gene expression together with quantitative PCR and Western blot analysis to identify dysregulation of genes and aberrant cellular processes in human fibroblasts and in SH-SY5Y neuroblastoma cells made HPRT-deficient by transduction with a retrovirus stably expressing an shRNA targeted against HPRT. An...
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Full title
HPRT Deficiency Coordinately Dysregulates Canonical Wnt and Presenilin-1 Signaling: A Neuro-Developmental Regulatory Role for a Housekeeping Gene?
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TN_cdi_plos_journals_1294222149
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1294222149
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0016572
