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Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose re...

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1294920834

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response

About this item

Full title

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-05, Vol.6 (5), p.e19527

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Although the efficacy of methadone maintenance treatment (MMT) in opioid dependence disorder has been well established, the influence of methadone pharmacokinetics in dose requirement and clinical outcome remains controversial. The aim of this study is to analyze methadone dosage in responder and nonresponder patients considering pharmacogenetic an...

Alternative Titles

Full title

Contribution of cytochrome P450 and ABCB1 genetic variability on methadone pharmacokinetics, dose requirements, and response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1294920834

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1294920834

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0019527

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