Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-ind...
Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Highly charged compounds typically suffer from low membrane permeability and thus are generally regarded as sub-optimal drug candidates. Nonetheless, the highly charged drug fosmidomycin and its more active methyl-derivative FR900098 have proven parasiticidal activity against erythrocytic stages of the malaria parasite Plasmodium falciparum. Both c...
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Full title
Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways
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TN_cdi_plos_journals_1295065562
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295065562
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0019334
