Automated high-content live animal drug screening using C. elegans expressing the aggregation prone...
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
The development of preclinical models amenable to live animal bioactive compound screening is an attractive approach to discovering effective pharmacological therapies for disorders caused by misfolded and aggregation-prone proteins. In general, however, live animal drug screening is labor and resource intensive, and has been hampered by the lack o...
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Full title
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z
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TN_cdi_plos_journals_1295221884
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295221884
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0015460
