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Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295222075

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

About this item

Full title

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2010-11, Vol.5 (11), p.e13959

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Insulin resistance is manifested in muscle, adipose tissue, and liver and is associated with adipose tissue inflammation. The cellular components and mechanisms that regulate the onset of diet-induced insulin resistance are not clearly defined.
We initially observed osteopontin (OPN) mRNA over-expression in adipose tissue of obese, insulin resis...

Alternative Titles

Full title

Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1295222075

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295222075

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0013959

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