Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice
Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Insulin resistance is manifested in muscle, adipose tissue, and liver and is associated with adipose tissue inflammation. The cellular components and mechanisms that regulate the onset of diet-induced insulin resistance are not clearly defined.
We initially observed osteopontin (OPN) mRNA over-expression in adipose tissue of obese, insulin resis...
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Full title
Osteopontin is required for the early onset of high fat diet-induced insulin resistance in mice
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TN_cdi_plos_journals_1295222075
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295222075
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0013959