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Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295609092

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

About this item

Full title

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-03, Vol.6 (3), p.e14757

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Picropodophyllin (PPP) is a promising novel anti-neoplastic agent that efficiently kills tumor cells in vitro and causes tumor regression and increased survival in vivo. We have previously reported that PPP treatment induced moderate tolerance in two out of 10 cell lines only, and here report the acquired genomic and expression alterations associat...

Alternative Titles

Full title

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1295609092

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295609092

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0014757