A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent gliobla...
A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Extracellular Hsp90 protein (eHsp90) potentiates cancer cell motility and invasion through a poorly understood mechanism involving ligand mediated function with its cognate receptor LRP1. Glioblastoma multiforme (GBM) represents one of the most aggressive and lethal brain cancers. The receptor tyrosine kinase EphA2 is overexpressed in the majority...
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Full title
A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
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TN_cdi_plos_journals_1295913401
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1295913401
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0017649
