Polyfunctional T-Cell Responses Are Disrupted by the Ovarian Cancer Ascites Environment and Only Par...
Polyfunctional T-Cell Responses Are Disrupted by the Ovarian Cancer Ascites Environment and Only Partially Restored by Clinically Relevant Cytokines
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Host T-cell responses are associated with favorable outcomes in epithelial ovarian cancer (EOC), but it remains unclear how best to promote these responses in patients. Toward this goal, we evaluated a panel of clinically relevant cytokines for the ability to enhance multiple T-cell effector functions (polyfunctionality) in the native tumor environ...
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Polyfunctional T-Cell Responses Are Disrupted by the Ovarian Cancer Ascites Environment and Only Partially Restored by Clinically Relevant Cytokines
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TN_cdi_plos_journals_1296211586
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296211586
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0015625
