A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic de...
A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
RNA interference (RNAi) is a powerful strategy for studying the phenotypic consequences of reduced gene expression levels in model systems. To develop a method for the rapid characterization of the developmental consequences of gene dysregulation, we tested the use of RNAi for "transient transgenic" knockdown of mRNA in mouse embryos. These methods...
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Full title
A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development
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TN_cdi_plos_journals_1296219192
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296219192
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0014375
