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Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296300301

Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

About this item

Full title

Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Publisher

San Francisco: Public Library of Science

Journal title

PloS one, 2010-12, Vol.5 (12), p.e15805

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein localization, transcription, DNA replication, and mitosis. Sumo conjugation is initiated by the hetero...

Alternative Titles

Full title

Crystal Structure of UBA2ufd-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1296300301

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296300301

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0015805

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