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Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1

Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296308855

Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1

About this item

Full title

Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-02, Vol.6 (2), p.e17010-e17010

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

DSCR1/ RCAN1 is a chromosome 21 gene found to be overexpressed in the brains of Down syndrome (DS) and postulated as a good candidate to contribute to mental disability. However, even though Rcan1 knockout mice have pronounced spatial learning and memory deficits, the possible deleterious effects of its overexpression in DS are not well understood....

Alternative Titles

Full title

Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1296308855

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1296308855

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0017010

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