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SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298101870

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

About this item

Full title

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2011-01, Vol.9 (1), p.e1000581-e1000581

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

As nascent polypeptide chains are synthesized, they pass through a tunnel in the large ribosomal subunit. Interaction between specific nascent chains and the ribosomal tunnel is used to induce translational stalling for the regulation of gene expression. One well-characterized example is the Escherichia coli SecM (secretion monitor) gene product, w...

Alternative Titles

Full title

SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1298101870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298101870

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1000581

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