An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secre...
An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secretion
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The generation of diversity and plasticity of transcriptional programs are key components of effective vertebrate immune responses. The role of Alternative Splicing has been recognized, but it is underappreciated and poorly understood as a critical mechanism for the regulation and fine-tuning of physiological immune responses. Here we report the ge...
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Full title
An shRNA-based screen of splicing regulators identifies SFRS3 as a negative regulator of IL-1β secretion
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TN_cdi_plos_journals_1298593487
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298593487
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0019829
