Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynth...
Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
About this item
Full title
Author / Creator
Blanc, Mathieu , Hsieh, Wei Yuan , Robertson, Kevin A. , Watterson, Steven , Shui, Guanghou , Lacaze, Paul , Khondoker, Mizanur , Dickinson, Paul , Sing, Garwin , Rodríguez-Martín, Sara , Phelan, Peter , Forster, Thorsten , Strobl, Birgit , Müller, Matthias , Riemersma, Rudolph , Osborne, Timothy , Wenk, Markus R. , Angulo, Ana and Ghazal, Peter
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Little is known about the protective role of inflammatory processes in modulating lipid metabolism in infection. Here we report an intimate link between the innate immune response to infection and regulation of the sterol metabolic network characterized by down-regulation of sterol biosynthesis by an interferon regulatory loop mechanism. In time-se...
Alternative Titles
Full title
Host Defense against Viral Infection Involves Interferon Mediated Down-Regulation of Sterol Biosynthesis
Authors, Artists and Contributors
Author / Creator
Hsieh, Wei Yuan
Robertson, Kevin A.
Watterson, Steven
Shui, Guanghou
Lacaze, Paul
Khondoker, Mizanur
Dickinson, Paul
Sing, Garwin
Rodríguez-Martín, Sara
Phelan, Peter
Forster, Thorsten
Strobl, Birgit
Müller, Matthias
Riemersma, Rudolph
Osborne, Timothy
Wenk, Markus R.
Angulo, Ana
Ghazal, Peter
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1298974852
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1298974852
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1000598
