Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Ris...
Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer
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Author / Creator
Maxwell, Christopher A. , Benítez, Javier , Gómez-Baldó, Laia , Osorio, Ana , Bonifaci, Núria , Fernández-Ramires, Ricardo , Costes, Sylvain V. , Guinó, Elisabet , Chen, Helen , Evans, Gareth J. R. , Mohan, Pooja , Català, Isabel , Petit, Anna , Aguilar, Helena , Villanueva, Alberto , Aytes, Alvaro , Serra-Musach, Jordi , Rennert, Gad , Lejbkowicz, Flavio , Peterlongo, Paolo , Manoukian, Siranoush , Peissel, Bernard , Ripamonti, Carla B. , Bonanni, Bernardo , Viel, Alessandra , Allavena, Anna , Bernard, Loris , Radice, Paolo , Friedman, Eitan , Kaufman, Bella , Laitman, Yael , Dubrovsky, Maya , Milgrom, Roni , Jakubowska, Anna , Cybulski, Cezary , Gorski, Bohdan , Jaworska, Katarzyna , Durda, Katarzyna , Sukiennicki, Grzegorz , Lubiński, Jan , Shugart, Yin Yao , Domchek, Susan M. , Letrero, Richard , Weber, Barbara L. , Hogervorst, Frans B. L. , Rookus, Matti A. , Collee, J. Margriet , Devilee, Peter , Ligtenberg, Marjolijn J. , van der Luijt, Rob B. , Aalfs, Cora M. , Waisfisz, Quinten , Wijnen, Juul , van Roozendaal, Cornelis E. P. , Easton, Douglas F. , Peock, Susan , Cook, Margaret , Oliver, Clare , Frost, Debra , Harrington, Patricia , Evans, D. Gareth , Lalloo, Fiona , Eeles, Rosalind , Izatt, Louise , Chu, Carol , Eccles, Diana , Douglas, Fiona , Brewer, Carole , Nevanlinna, Heli , Heikkinen, Tuomas , Couch, Fergus J. , Lindor, Noralane M. , Wang, Xianshu , Godwin, Andrew K. , Caligo, Maria A. , Lombardi, Grazia , Loman, Niklas , Karlsson, Per , Ehrencrona, Hans , von Wachenfeldt, Anna , Bjork Barkardottir, Rosa , Hamann, Ute , Rashid, Muhammad U. , Lasa, Adriana , Caldés, Trinidad , Andrés, Raquel , Schmitt, Michael , Assmann, Volker , Stevens, Kristen , Offit, Kenneth , Curado, João , Tilgner, Hagen , Guigó, Roderic , Aiza, Gemma , Brunet, Joan , Castellsagué, Joan , Martrat, Griselda , Urruticoechea, Ander , Blanco, Ignacio , Tihomirova, Laima , HEBON , EMBRACE , GEMO Study Collaborators , kConFab , BCFR , SWE-BRCA , Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States) , Faculty of Medicine , Department of Clinical Sciences, Lund , Medicinska fakulteten , Lund University , Bröstcancer-genetik , Institutionen för kliniska vetenskaper, Lund , Section I , Breastcancer-genetics , Lunds universitet and Sektion I
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal breast tissue and increased risk of developing tumors of basal-like type suggest that BRCA1 regulates stem/progenitor cell prolife...
Alternative Titles
Full title
Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer
Authors, Artists and Contributors
Author / Creator
Benítez, Javier
Gómez-Baldó, Laia
Osorio, Ana
Bonifaci, Núria
Fernández-Ramires, Ricardo
Costes, Sylvain V.
Guinó, Elisabet
Chen, Helen
Evans, Gareth J. R.
Mohan, Pooja
Català, Isabel
Petit, Anna
Aguilar, Helena
Villanueva, Alberto
Aytes, Alvaro
Serra-Musach, Jordi
Rennert, Gad
Lejbkowicz, Flavio
Peterlongo, Paolo
Manoukian, Siranoush
Peissel, Bernard
Ripamonti, Carla B.
Bonanni, Bernardo
Viel, Alessandra
Allavena, Anna
Bernard, Loris
Radice, Paolo
Friedman, Eitan
Kaufman, Bella
Laitman, Yael
Dubrovsky, Maya
Milgrom, Roni
Jakubowska, Anna
Cybulski, Cezary
Gorski, Bohdan
Jaworska, Katarzyna
Durda, Katarzyna
Sukiennicki, Grzegorz
Lubiński, Jan
Shugart, Yin Yao
Domchek, Susan M.
Letrero, Richard
Weber, Barbara L.
Hogervorst, Frans B. L.
Rookus, Matti A.
Collee, J. Margriet
Devilee, Peter
Ligtenberg, Marjolijn J.
van der Luijt, Rob B.
Aalfs, Cora M.
Waisfisz, Quinten
Wijnen, Juul
van Roozendaal, Cornelis E. P.
Easton, Douglas F.
Peock, Susan
Cook, Margaret
Oliver, Clare
Frost, Debra
Harrington, Patricia
Evans, D. Gareth
Lalloo, Fiona
Eeles, Rosalind
Izatt, Louise
Chu, Carol
Eccles, Diana
Douglas, Fiona
Brewer, Carole
Nevanlinna, Heli
Heikkinen, Tuomas
Couch, Fergus J.
Lindor, Noralane M.
Wang, Xianshu
Godwin, Andrew K.
Caligo, Maria A.
Lombardi, Grazia
Loman, Niklas
Karlsson, Per
Ehrencrona, Hans
von Wachenfeldt, Anna
Bjork Barkardottir, Rosa
Hamann, Ute
Rashid, Muhammad U.
Lasa, Adriana
Caldés, Trinidad
Andrés, Raquel
Schmitt, Michael
Assmann, Volker
Stevens, Kristen
Offit, Kenneth
Curado, João
Tilgner, Hagen
Guigó, Roderic
Aiza, Gemma
Brunet, Joan
Castellsagué, Joan
Martrat, Griselda
Urruticoechea, Ander
Blanco, Ignacio
Tihomirova, Laima
HEBON
EMBRACE
GEMO Study Collaborators
kConFab
BCFR
SWE-BRCA
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Faculty of Medicine
Department of Clinical Sciences, Lund
Medicinska fakulteten
Lund University
Bröstcancer-genetik
Institutionen för kliniska vetenskaper, Lund
Section I
Breastcancer-genetics
Lunds universitet
Sektion I
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1299057632
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1299057632
Other Identifiers
ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001199
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