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IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigare...

IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigare...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1299061038

IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

About this item

Full title

IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-05, Vol.6 (5), p.e20333

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Chronic Obstructive Pulmonary Disease (COPD) is characterized by airspace enlargement and peribronchial lymphoid follicles; however, the immunological mechanisms leading to these pathologic changes remain undefined. Here we show that cigarette smoke is a selective adjuvant that augments in vitro and in vivo Th17, but not Th1, cell differentiation v...

Alternative Titles

Full title

IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1299061038

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1299061038

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0020333

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