Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of I...
Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
For several decades, molecular recognition has been considered one of the most fundamental processes in biochemistry. For enzymes, substrate binding is often coupled to conformational changes that alter the local environment of the active site to align the reactive groups for efficient catalysis and to reach the transition state. Adaptive substrate...
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Full title
Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis
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TN_cdi_plos_journals_1299067052
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1299067052
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1001066
