LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromat...
LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromatid Cohesion
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Successful execution of the meiotic program depends on the timely establishment and removal of sister chromatid cohesion. LAB-1 has been proposed to act in the latter by preventing the premature removal of the meiosis-specific cohesin REC-8 at metaphase I in C. elegans, yet the mechanism and scope of LAB-1 function remained unknown. Here we identif...
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LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromatid Cohesion
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TN_cdi_plos_journals_1303595876
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1303595876
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1545-7885,1544-9173
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1545-7885
DOI
10.1371/journal.pbio.1001378