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Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1303893516

Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

About this item

Full title

Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2012-11, Vol.10 (11), p.e1001429

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The modulation of pentameric ligand-gated ion channels (pLGICs) by divalent cations is believed to play an important role in their regulation in a physiological context. Ions such as calcium or zinc influence the activity of pLGIC neurotransmitter receptors by binding to their extracellular domain and either potentiate or inhibit channel activation...

Alternative Titles

Full title

Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1303893516

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1303893516

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1001429

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