Matrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmaco...
Matrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmacokinetics of anti-cancer drug 5-Fluorouracil
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Concurrent chemoradiation with 5-fluorouracil (5-FU) is widely accepted for cancer treatment. However, the interactions between radiation and 5-FU remain unclear. Here, we evaluated the influence of local irradiation on the pharmacokinetics of 5-FU in rats. The single-fraction radiation was delivered to the whole pelvic fields of Sprague-Dawley rat...
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Full title
Matrix metalloproteinase-8 mediates the unfavorable systemic impact of local irradiation on pharmacokinetics of anti-cancer drug 5-Fluorouracil
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TN_cdi_plos_journals_1304770774
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304770774
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0021000
