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Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embr...

Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304889385

Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells

About this item

Full title

Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-06, Vol.6 (6), p.e20820

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Dominant mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most prevalent cause of Parkinson's disease, however, little is known about the biological function of LRRK2 protein. LRRK2 is expressed in neural precursor cells suggesting a role in neurodevelopment.
In the present study, differential gene expression profiling revealed...

Alternative Titles

Full title

Leucine-rich repeat kinase 2 modulates retinoic acid-induced neuronal differentiation of murine embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1304889385

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1304889385

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0020820

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