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Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1305757039

Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

About this item

Full title

Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011-07, Vol.6 (7), p.e22568

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Biogenic amines have been demonstrated to protect cells from apoptotic cell death. Herein we show for the first time that serotonin and dopamine increase H(2)S production by the endogenous enzyme cystathionine-β-synthase (CBS) and protect cells against hypothermia/rewarming induced reactive oxygen species (ROS) formation and apoptosis. Treatment wi...

Alternative Titles

Full title

Serotonin and Dopamine Protect from Hypothermia/Rewarming Damage through the CBS/ H2S Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1305757039

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1305757039

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0022568

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