Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and meta...
Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Overproduction of amyloid-β (Aβ) protein in the brain has been hypothesized as the primary toxic insult that, via numerous mechanisms, produces cognitive deficits in Alzheimer's disease (AD). Cholinesterase inhibition is a primary strategy for treatment of AD, and specific compounds of this class have previously been demonstrated to influence Aβ pr...
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Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons
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TN_cdi_plos_journals_1306134957
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306134957
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0021954
