Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Cer...
Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide
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Author / Creator
Spijkers, Léon J. A. , van den Akker, Rob F. P. , Janssen, Ben J. A. , Debets, Jacques J. , De Mey, Jo G. R. , Stroes, Erik S. G. , van den Born, Bert-Jan H. , Wijesinghe, Dayanjan S. , Chalfant, Charles E. , MacAleese, Luke , Eijkel, Gert B. , Heeren, Ron M. A. , Alewijnse, Astrid E. and Peters, Stephan L. M.
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Hypertension is, amongst others, characterized by endothelial dysfunction and vascular remodeling. As sphingolipids have been implicated in both the regulation of vascular contractility and growth, we investigated whether sphingolipid biology is altered in hypertension and whether this is reflected in altered vascular function.
In isolated carot...
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Full title
Hypertension Is Associated with Marked Alterations in Sphingolipid Biology: A Potential Role for Ceramide
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Record Identifier
TN_cdi_plos_journals_1306248410
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306248410
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0021817
