A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children
A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children
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Full title
Author / Creator
Bélard, Sabine , Issifou, Saadou , Hounkpatin, Aurore B. , Schaumburg, Frieder , Ngoa, Ulysse Ateba , Esen, Meral , Fendel, Rolf , de Salazar, Pablo Martinez , Mürbeth, Raymund E. , Milligan, Paul , Imbault, Nathalie , Imoukhuede, Egeruan Babatunde , Theisen, Michael , Jepsen, Søren , Noor, Ramadhani A. , Okech, Brenda , Kremsner, Peter G. and Mordmüller, Benjamin
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
GMZ2 is a fusion protein of Plasmodium falciparum merozoite surface protein 3 (MSP3) and glutamate rich protein (GLURP) that mediates an immune response against the blood stage of the parasite. Two previous phase I clinical trials, one in naïve European adults and one in malaria-exposed Gabonese adults showed that GMZ2 was well tolerated and immuno...
Alternative Titles
Full title
A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children
Authors, Artists and Contributors
Author / Creator
Issifou, Saadou
Hounkpatin, Aurore B.
Schaumburg, Frieder
Ngoa, Ulysse Ateba
Esen, Meral
Fendel, Rolf
de Salazar, Pablo Martinez
Mürbeth, Raymund E.
Milligan, Paul
Imbault, Nathalie
Imoukhuede, Egeruan Babatunde
Theisen, Michael
Jepsen, Søren
Noor, Ramadhani A.
Okech, Brenda
Kremsner, Peter G.
Mordmüller, Benjamin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1306360761
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306360761
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0022525
