Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death
Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Granzyme-mediated cell death is the major pathway for cytotoxic lymphocytes to kill virus-infected and tumor cells. In humans, five different granzymes (i.e. GrA, GrB, GrH, GrK, and GrM) are known that all induce cell death. Expression of intracellular serine protease inhibitors (serpins) is one of the mechanisms by which tumor cells evade cytotoxi...
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Full title
Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death
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TN_cdi_plos_journals_1306886622
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1306886622
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0022645
