The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation...
The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Gliomas are the most frequently occurring primary brain tumor in the central nervous system of adults. Glioblastoma multiformes (GBMs, WHO grade 4) have a dismal prognosis despite the use of the alkylating agent, temozolomide (TMZ), and even low grade gliomas (LGGs, WHO grade 2) eventually transform to malignant secondary GBMs. Although GBM patient...
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Full title
The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma
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TN_cdi_plos_journals_1307257638
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307257638
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023332
