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MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Bru...

MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Bru...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307259721

MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Brucella abortus Infection

About this item

Full title

MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Brucella abortus Infection

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011, Vol.6 (8), p.e23135-e23135

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Type I interferons (IFNs) are cytokines that orchestrate diverse immune responses to viral and bacterial infections. Although typically considered to be most important molecules in response to viruses, type I IFNs are also induced by most, if not all, bacterial pathogens. In this study, we addressed the role of type I IFN signaling during Brucella...

Alternative Titles

Full title

MyD88 and STING Signaling Pathways Are Required for IRF3-Mediated IFN-β Induction in Response to Brucella abortus Infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1307259721

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307259721

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0023135

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