A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific...
A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The vaccinia virus (VACV) C6 protein has sequence similarities with the poxvirus family Pox_A46, involved in regulation of host immune responses, but its role is unknown. Here, we have characterized the C6 protein and its effects in virus replication, innate immune sensing and immunogenicity in vivo. C6 is a 18.2 kDa protein, which is expressed ear...
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Full title
A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses
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TN_cdi_plos_journals_1307791995
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1307791995
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0024244
