MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian R...
MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian Rat Model
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Human embryonic stem cells (hESCs) can potentially differentiate into any cell type, including dopaminergic neurons to treat Parkinson's disease (PD), but hyperproliferation and tumor formation must be avoided. Accordingly, we use myocyte enhancer factor 2C (MEF2C) as a neurogenic and anti-apoptotic transcription factor to generate neurons from hES...
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MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian Rat Model
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TN_cdi_plos_journals_1308020768
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308020768
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0024027
