Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The DNA methylation inhibitor 5-aza-2'-deoxycytidine (DAC) is approved for the treatment of myelodysplastic syndromes (MDS), but resistance to DAC develops during treatment and mechanisms of resistance remain unknown. Therefore, we investigated mechanisms of primary and secondary resistance to DAC in MDS.
We performed Quantitative Real-Time PCR...
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Full title
Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
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TN_cdi_plos_journals_1308334932
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308334932
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0023372
