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Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronical...

Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronical...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308335457

Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronically Infected Cells via Activation of RhoA and PKCε

About this item

Full title

Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronically Infected Cells via Activation of RhoA and PKCε

Publisher

United States: Public Library of Science

Journal title

PloS one, 2011, Vol.6 (8), p.e23674

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

More information

Scope and Contents

Contents

HIV replication in mononuclear phagocytes is a multi-step process regulated by viral and cellular proteins with the peculiar feature of virion budding and accumulation in intra-cytoplasmic vesicles. Interaction of urokinase-type plasminogen activator (uPA) with its cell surface receptor (uPAR) has been shown to favor virion accumulation in such sub...

Alternative Titles

Full title

Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronically Infected Cells via Activation of RhoA and PKCε

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1308335457

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308335457

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0023674

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