Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliora...
Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Previous studies have shown that inducing autophagy ameliorates early cognitive deficits associated with the build-up of soluble amyloid-β (Aβ). However, the effects of inducing autophagy on plaques and tangles are yet to be determined. While soluble Aβ and tau represent toxic species in Alzheimer's disease (AD) pathogenesis, there is well document...
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Inducing Autophagy by Rapamycin Before, but Not After, the Formation of Plaques and Tangles Ameliorates Cognitive Deficits
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TN_cdi_plos_journals_1308858303
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308858303
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1932-6203
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1932-6203
DOI
10.1371/journal.pone.0025416
